Amyotrophic Lateral Sclerosis

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Long-Term Tofersen Therapy in SOD1-ALS: Early Initiation Preserves Function and Extends Survival

By MedXY|Feb 11, 2026

The integrated analysis of the VALOR trial and its open-label extension reveals that early initiation of tofersen significantly slows functional decline, preserves respiratory capacity, and improves survival in patients with SOD1-ALS over a

NeurologyAmyotrophic Lateral Sclerosisepidemiology

Unraveling the Link Between Traumatic Brain Injury and ALS Risk: Insights From a Large UK Cohort Study

By MedXY|Oct 5, 2025

A large retrospective cohort study reveals a transient association between traumatic brain injury (TBI) and elevated amyotrophic lateral sclerosis (ALS) risk, suggesting early ALS symptoms may predispose to injury rather than TBI causing AL