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Brain Imaging Biomarkers and Cognitive Outcomes in a Multidomain Lifestyle Intervention: The POINTER Imaging Ancillary Study

The POINTER Imaging study found no overall brain biomarker changes from a structured lifestyle intervention, but participants with lower baseline hippocampal volume showed greater cognitive benefit, suggesting imaging may help identify who

Tau Links Amyloid and Vascular Burden to Faster Clinical Decline: Chronicity Reveals Synergy Between White Matter Injury and Amyloid in Dementia Progression