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alcohol-associated liver disease

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KIF13B-KPNA2-PPARα Axis: A Novel Target for Mitigating Alcohol-Associated Liver Steatosis

Emerging evidence identifies KIF13B facilitating KPNA2-mediated nuclear import of PPARα as a critical mechanism to mitigate alcohol-associated liver steatosis, highlighting novel therapeutic strategies for ALD.

Aug 22, 2026
Clinical Updates

Uncovering the Hepatocyte CEBPA-ORM1 Axis: A Novel Regulatory Pathway and Biomarker in Alcohol-Associated Liver Disease

This review synthesizes recent findings identifying the CEBPA-ORM1 axis as a critical suppressor of alcohol-associated liver disease, highlighting its potential as both a therapeutic target and a diagnostic biomarker for disease staging.

Mar 10, 2026Sign in to read
Gastroenterology

Cutting the Curve: Consensus Strategies to Reduce Alcohol‑Associated Liver Disease in the Population

A concise synthesis of a 2025 multistakeholder Lancet workshop consensus on population and clinical strategies to prevent, detect, and manage alcohol‑associated liver disease.

Nov 9, 2025

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