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A comprehensive cohort study demonstrates that ADHD significantly increases the risk of mild cognitive impairment and dementia in older adults, highlighting the need for targeted monitoring and integrated care in this vulnerable population.
A Danish cohort study reveals decreased genetic risk profiles in recent ASD and ADHD diagnoses, supporting broader diagnostic criteria as a driver of rising incidence rates.
This review synthesizes current evidence on the impact of continuing psychostimulant treatment during pregnancy on postpartum mental health outcomes among people with ADHD, highlighting key findings and clinical implications from recent lar
A large sibling-matched cohort study found no link between prenatal acetaminophen exposure and autism or ADHD, suggesting prior associations were confounded by familial factors and supporting the safety of indicated paracetamol use during p
In a nationwide Finnish cohort, earlier ADHD diagnosis was linked to better school performance, more academic progression, and less dropout than diagnosis closer to age 16, especially before educational track selection.
This review explores a groundbreaking study using normative modeling and morphometric similarity networks to identify three distinct neurobiological biotypes of ADHD, providing a framework for precision psychiatry.
A 46-year longitudinal study reveals that childhood ADHD traits significantly predict higher rates of physical health conditions, multimorbidity, and disability by middle age, mediated by modifiable risk factors like smoking, BMI, and psych
This large-scale individual participant data meta-analysis of 76,514 children reveals that prenatal maternal depression is significantly associated with increased risks of ADHD, ASD, and behavioral symptoms, independent of pre-pregnancy dep
Recent large-scale cohort studies suggest that previously observed links between prenatal exposure to acid-suppressants or antipsychotics and neurodevelopmental disorders are largely due to familial confounding. Conversely, active maternal
A comprehensive BMJ umbrella review synthesizes evidence for ADHD interventions across the lifespan, confirming the efficacy of stimulants and non-stimulants in the short term while revealing a critical lack of high-certainty long-term data
Updated Cochrane analysis (212 RCTs, 16,302 participants) finds methylphenidate may reduce teacher-rated ADHD symptoms and improve general behaviour but increases non‑serious adverse events; overall evidence certainty is very low.
An umbrella review of systematic reviews finds low to critically low confidence in studies linking prenatal paracetamol exposure to autism or ADHD; sibling-controlled analyses largely attenuate associations. Clinical guidance: use lowest ef
This study evaluates whether initiating ADHD stimulant prescriptions via telehealth affects later risks of stimulant or other substance use disorders, finding no SUD risk increase but a potential rise in stimulant use disorder risk.
This study analyzes the diagnosis and medication initiation of ADHD among children aged 3-5 across multiple US health systems, highlighting sociodemographic disparities and clinical practices.
Stimulant use disorder diagnoses in young adult Medicaid enrollees have markedly increased from 2001 to 2020, especially for noncocaine psychostimulants, highlighting an urgent need for targeted interventions and evidence-based treatments a
Recent research reveals distinct gut microbial and metabolic profiles linked to ADHD symptoms, highlighting short-chain fatty acid deficiency as a key mechanism driving hyperactivity and inattention.
Pharmaceutical companies have significantly increased marketing payments to clinicians for ADHD medications, particularly targeting advanced practice clinicians. The impact of this trend on prescribing patterns and clinical benefits remains
The MADDY study reveals that micronutrient supplementation in children with ADHD alters gut microbial diversity and composition, notably increasing beneficial butyrate-producing bacteria, potentially underpinning improved behavioral outcome
A tailored, app-supported exercise program delivered via mobile health significantly improves core ADHD symptoms and executive functions in children, demonstrating comparable effectiveness to traditional face-to-face exercise guidance.
A randomized clinical trial demonstrates that an Acceptance and Commitment Therapy-based parenting program reduces health care use, improves asthma control, and alleviates ADHD symptoms in children with both conditions.
