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Noncontrast CT vs CT Perfusion Imaging in Acute Stroke: Comparative Insights from Recent Trials and Systematic Review

Recent evidence from randomized trials and meta-analyses suggests that noncontrast CT (NCCT) offers comparable outcome prediction to CT perfusion (CTP) for selecting patients with acute ischemic stroke, including basilar artery occlusion, f

Aug 17, 2025
Clinical Updates

Edaravone Dexborneol in Acute Ischemic Stroke: Real-World Evidence of Enhanced Functional Recovery and Safety

In a large multicenter cohort study, edaravone dexborneol treatment in acute ischemic stroke patients was linked to improved 90-day functional outcomes without increased adverse events, supporting its clinical utility.

Aug 17, 2025
Clinical Updates

JAMA: Extending Intravenous Alteplase to 24 Hours in Imaging‑Selected Ischemic Stroke (HOPE Trial)

The HOPE randomized trial shows that CT‑perfusion–selected patients treated with intravenous alteplase at 4.5–24 hours (no planned thrombectomy) had higher 90‑day functional independence (40.3% vs 26.3%), with increased symptomatic intracra

Aug 10, 2025
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