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Dapivirine Ring and Oral PrEP in Pregnancy: MTN-042/DELIVER Shows Infant Safety Through 12 Months

MedXY Editorial Team•Nov 12, 2025•HIV/AIDS
Pregnancy

Highlight

– MTN-042/DELIVER randomized pregnant, HIV-negative women to dapivirine vaginal ring (DVR) or daily oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) and followed 545 infants to 12 months.

– Composite infant safety events (serious adverse events or grade ≥3 adverse events) occurred but were not attributed to study product; no maternal or infant HIV infections were observed.

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